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Effectiveness of this treatment was poor and the mortality rate was high (about 80% of cases) ( 94). In infants 1 month to <3 months of age, mean acyclovir exposures resulting from a 25 mg/kg dose were higher (C max: ↑30%, AUC: ↑60%) than acyclovir exposures following a 1 gram dose of valacyclovir in adults.

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